On the eve of the IX Summit of the Americas, hosted by President Biden in Los Angeles, the United States announced the establishment of complementary mechanisms to bolster resiliency of the hemisphere’s health economies and ecosystems: the multisectoral Americas RISE for Health  and the Economic and Health Dialogue of the Americas (EHA) Together, RISE and EHA represent novel complementary efforts that focus the region’s governments, private sector and civil society on shared challenges and opportunities to build resilient, inclusive, sustainable, equitable (RISE) health economies and ecosystems.